![]() PAUSED or ABANDONED: If investigators observe worrying symptoms in volunteers, they can pause the trial. ![]() Some vaccines are now in Phase 1/2 trials, for example, which this tracker would count as both Phase 1 and Phase 2. Experts have warned of serious risks from jumping ahead of these results.ĪPPROVAL: Regulators review the complete trial results and plans for a vaccine’s manufacturing, and decide whether to give it full approval.ĬOMBINED PHASES: One way to accelerate vaccine development is to combine phases. In addition, some countries such as China and Russia began administering vaccines before detailed Phase 3 trial data was made public. Phase 3 trials are also large enough to reveal evidence of relatively rare side effects.ĮARLY OR LIMITED APPROVAL: Many countries have procedures for providing emergency authorizations for vaccines, based on preliminary evidence that they are safe and effective. These trials can determine if the vaccine protects against the coronavirus, measuring what’s known as the efficacy rate. PHASE 3 EFFICACY TRIALS: Scientists give the vaccine to thousands of people and wait to see how many become infected, compared with volunteers who received a placebo. These trials further test the vaccine’s safety. PHASE 2 EXPANDED TRIALS: Scientists give the vaccine to hundreds of people split into groups, such as children and the elderly, to see if the vaccine acts differently in them. ![]() ![]() PHASE 1 SAFETY TRIALS: Scientists give the vaccine to a small number of people to test safety and dosage, as well as to confirm that it stimulates the immune system. PRECLINICAL TESTING: Scientists test a new vaccine on cells and then give it to animals such as mice or monkeys to see if it produces an immune response. The development cycle of a vaccine, from lab to clinic. For an explanation of leading vaccines, see How Nine Covid-19 Vaccines Work. For treatments for Covid-19, see our Coronavirus Drug and Treatment Tracker. For an explanation of virus variants and mutations, see our Coronavirus Variant Tracker. The mayor of Wuhan has already faced scrutiny for allowing a massive Lunar New Year banquet - involving 40,000 families - to take place despite the spread of the virus.Below is a list of all vaccines that have reached trials in humans. "We may have blocked the disease, but we will all go down in history with a bad name," he admitted. In Hubei, Chinese authorities have stopped public transport in at least 18 cities in a bid to contain the deadly virus, while putting the capital - a city of 11 million inhabitants - under effective quarantine.Ĭlosing transport out of Wuhan was a "very difficult decision," added Zhou Xianwang, Wuhan's mayor, in an interview with state broadcaster CCTV on Monday. "We also feel very distressed and very guilty, and we also very much blame ourselves," said Wang at Sunday's press briefing. "As the governor of Hubei province, how can you not know how many masks Hubei province produces?" asked one incredulous user.Ĭentral Hubei province is at the heart of China's new virus outbreak, which has killed at least 81 people and infected more than 2,700 people across the country and has spread overseas, including Thailand, the United States, and Australia. Online users also zeroed in on Wang's repeated fumble of Hubei's annual mask production - giving three revisions to his answer from 10.8 billion to 1.8 billion, to 1.08 million. The comments are a rare instance of public anger outpacing the army of online censors in China, where criticism of government figures is usually scrubbed.īy Monday afternoon, a hashtag on the press briefing had more than 680 million views on Weibo. "Incompetent and irresponsible politicians," wrote another in a scathing comment about the press briefing. "If the mayor doesn't even know how to wear a mask, how will everyday people know?" criticised one user. Meanwhile the mayor of Wuhan was wearing his mask incorrectly by having it on inside out, pointed out Chinese users on Weibo, China's Twitter-like social media platform. Governor of central Hubei province Wang Xiaodong held the press conference without wearing a mask - in violation of the provincial capital Wuhan's own rules mandating masks in public spaces. Many Chinese netizens were incensed by what they perceived as a series of errors at a televised press conference Sunday by three local officials at the heart of the new virus outbreak. Beijing: Chinese officials at the epicentre of a health crisis are coming under fire for incompetence and being ridiculed for not properly wearing protective masks as anger mounts over the handling of a deadly virus.
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